Workaround solution if you don't want to deal with turning off/uninstalling the back program.
-With ComicBase closed, create a new sub-folder on your Local C Drive (ex: My ComicBase Databases)
-move your working database to this folder.
-once moved, simply double-click on your database itself from its new folder location and it'll load into ComicBase.
-immediately quit out of the software. When you start up the software from the ComicBase desktop icon, it'll load the database from its new location.
*if you use ComicBase Sidekick be sure to update the database list (Settings>general tab) so that your database is being accessed from its new folder location.